RESUMO
Purpose: The objective of this study was to evaluate if the carrageenan may be used for limiting the mandibular movement. Material and Methods: Eighteen adult male Wistar rats were used for the research, 20 ìl of carrageenan (4%) was infiltrated in the extra articular region, in front of the condyle to induce fibrosis. The rats were divided into groups according to the time of euthanasia (7, 15 and 30 days). Maximal mouth opening (MMO), mandibular deviation,initial and final weights were recorded and evaluated. After the euthanasia, the specimens were submitted to histological study in order to classify the inflammatory process using scores. Results: The mean differences between initial and final MMO were 1.50 mm, being greatest at the 7 days evaluation and lowest at 30 days, and were not statistically significant at any time. No mandibular deviation was observedat any of the times of evaluation. The histological scores tended to increase with time of evaluation from 7to 30 days, but without progression of the process.Conclusion: The study model permitted the development of fibrosis in the extra-articular region in the majority of the animals (AU)
Assuntos
Animais , Transtornos da Articulação Temporomandibular/cirurgia , Carragenina/uso terapêutico , Modelos Animais , Ratos Wistar/cirurgiaRESUMO
El ameloblastoma es un tumor de epitelio odontogénico, caracterizado por la invasión local y aumento de la tasa de recidiva. Por esto se realizó este estudio descriptivo para determinar el comportamiento de los ameloblastomas en nuestro medio. Método: estudio retrospectivo de 17 años basado en los datos existentes de los archivos del Departamento Oral de Patología. Se analizaron los archivos de pacientes de enero de 1992 a mayo de 2009, con un diagnóstico definitivo de ameloblastoma. Fué recogida la información respecto al sexo, raza, presencia de síntomas, ubicación anatómica y extensión. Resultados: dentro de los 60 pacientes con ameloblastoma se observó, mayor incidencia en la tercera década de vida (28,3 por ciento). Las mujeres fueron más comprometidas que los hombres, con una proporción 1,22:1. La mayoría de lesiones fueron observadas en la raza blanca (51,7 por ciento). El sitio más habitual por la ocurrencia de tumor fue la mandíbula (85 por ciento). Los pacientes fueron sintomáticos en el 75 por ciento. La mayoría de pacientes presentaron lesiones de 3,5 a 6,0 centímetros de extensión (55 por ciento). Conclusiones: el ameloblastoma es mayormente observado en mujeres, en la tercera década de la vida y en la mandíbula. Las diferencias con otros estudios entre el sexo, la edad, raza, extensión, localización anatómica y los síntomas pueden ser atribuidos a las diferencias geográficas(AU)
The ameloblastoma is a tumor originated from odontogenic epithelium, characterized by local invasion and increased rates of recurrence. Methods: The 17-year retrospective study was based on existing data from the archives of Oral Pathology Department. Files of patients of January 1992-May 2009 with a definitive diagnostic of ameloblastoma were assessed. Information regarding gender, race, presence of symptoms, anatomic location and extent was documented. Results: Within the 60 patients with ameloblastoma observed, the age peak of tumor incidence was the third decade of life (28.3 percent). Females were more prominent than males, with a ratio 1.22:1. The majority of lesions were showed in Caucasians patients (51.7 percent). The most prevalent site for tumor occurrence was the mandible (85 percent). Symptomatic patients performed a total of 75 percent. The majority of patients had lesions from 3.5 to 6.0 cm of extension (55 percent). Conclusions: The ameloblastoma is more observed in females, in the third decade of life and in the mandible. The differences with other studies between gender, age, race, extent, anatomic location and symptoms can be attributed to geographic variations(AU)
